ANTIMICROBIAL ACTIVITY AND THE MEDIAN LETHAL DOSE OF DILL (Anethum Graveolens ) EXTRACT .

Abstract

Antimicrobial activities of dill (Anethum graveolens) extract were studied by agar well diffusion technique against tested organisms (Staphylococcus aureus, Esherichia coli and Candida albicans), which were streaking onto agar plates and incubated for 16-20 hours at 37°C. The results were showed that the extract did not show antibacterial activity, while the extract of dill seeds exhibited growth inhibition of C. albicans. The results were also showed that the median lethal dose (LD50) of the ethanolic extract of dill in laboratory white mice was about (1486 mg/kg Bodyweight B.W ). The clinical signs during 24 hours after subcutaneous injection of the extract were rapid breathing, dullness, then death.